| Identification | Back Directory | [Name]
APcK110 | [CAS]
1001083-74-4 | [Synonyms]
APcK110
6-(3,5-Dimethoxyphenyl)-3-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine
1H-Pyrazolo[3,4-b]pyridine, 6-(3,5-dimethoxyphenyl)-3-(4-fluorophenyl)- | [Molecular Formula]
C20H16FN3O2 | [MOL File]
1001083-74-4.mol | [Molecular Weight]
349.36 |
| Hazard Information | Back Directory | [Uses]
APcK 110 induces apoptosis and inhibits proliferation of acute myeloid leukemia cells. | [in vivo]
APcK110 (500 nM; i.p.; every other day for 60 days) shows anti-AML activity in mice[2]. | Animal Model: | Eight-weeks-old female NODSCID mice, OCI/AML3 xenograft mouse model[2] | | Dosage: | 500 nM | | Administration: | Intraperitoneal injection, every other day for 60 days | | Result: | Survival of compound-treated mice was significantly longer compared with mice injected with PBS. |
|
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
|