| Identification | Back Directory | [Name]
GSK369796 | [CAS]
1010411-21-8 | [Synonyms]
CS-2373
GSK369796
GSK369796 HCL
GSK369796 2HCl
N-tert-butylisoquine
GSK 369796; GSK-369796
GSK369796 Dihydrochloride
GSK369796 (GSK-369796, GSK 369796)
5-[(7-Chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]phenol Hydrochloride
Phenol, 5-[(7-chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]-, hydrochloride | [Molecular Formula]
C20H24Cl3N3O | [MDL Number]
MFCD16627991 | [MOL File]
1010411-21-8.mol | [Molecular Weight]
428.783 |
| Chemical Properties | Back Directory | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
DMSO:100.0(Max Conc. mg/mL);233.22(Max Conc. mM)
Water:50.0(Max Conc. mg/mL);116.61(Max Conc. mM) | [form ]
A solid | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
5-[(7-Chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]phenol Hydrochloride is an effective aminoquinoline antimalarial. | [in vivo]
In vivo, GSK369796 Dihydrochloride can inhibit the growth of Plasmodium berghei ANKA with ED50 and ED90 of 2.8 and 4.7 mg/kg, respectively[1]. | [IC 50]
Plasmodium |
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