| Identification | Back Directory | [Name]
N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide | [CAS]
1100353-03-4 | [Synonyms]
CASP3 Activator 1541
Procaspase-3 activator 1541
N-(3-imidazo[1,2-a]pyridin-2-ylphenyl)-8-methoxy-2-oxochromene-3-carboxamide
N-(3-(iMidazo[1,2-a]pyridin-2-yl)phenyl)-8-Methoxy-2-oxo-2H-chroMene-3-carboxaMide | [Molecular Formula]
C24H17N3O4 | [MDL Number]
MFCD12020897 | [MOL File]
1100353-03-4.mol | [Molecular Weight]
411.41 |
| Hazard Information | Back Directory | [Uses]
Procaspase-3/6 activator 1 (compound 1541) is a highly specific and robust activator of executioner procaspases-3 and -6, with EC50 values of 2.4 ± 0.2 and 2.8 ± 0.3 μM, respectively. Procaspase-3/6 activator 1 does not activate procaspases-1 or -7[1]. | [IC 50]
Procaspase-3: 2.4 ± 0.2 μM (EC50); Procaspase-6: 2.8 ± 0.3 μM (EC50) | [References]
[1] Wolan DW, et al. Small-molecule activators of a proenzyme. Science. 2009 Nov 6;326(5954):853-8. DOI:10.1126/science.1177585 |
|
| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
| Company Name: |
cjbscvictory
|
| Tel: |
13348960310 13348960310 |
| Website: |
https://www.weikeqi-biotech.com/ |
|