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Ono 1082 is a drug that increases cAMP levels in hepatocytes in rats. | [Uses]
ONO 1082 is a Prostaglandin E1 (PGE1) (HY-B0131) derivative and increases cAMP level in hepatocytes. ONO 1082 competes with the action of the cholestatic factor through the increase in the cAMP level[1]. | [References]
[1] Kioka K, et al. [Effects of the cholestatic factor and the prostaglandin E1 derivative on the level of cAMP in isolated hepatocytes of rats]. Nihon Shokakibyo Gakkai Zasshi. 1989 Jan;86(1):45-9. Japanese. PMID:2543851 |
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