113-18-8

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113-18-8 Structure

Chemical Properties	Back Directory
[Melting point ] 25°C
[Boiling point ] bp760 173-174°; also reported as bp760 181°; bp0.1 28.5-30°
[density ] d425 1.065-1.070; also reported as d420 1.070
[refractive index ] nD25 1.4675-1.4800

Hazard Information	Back Directory
[Chemical Properties] Clear Colorless Oil
[Uses] Controlled substance (depressant). Sedative; hypnotic.
[Definition] ChEBI: Propargyl alcohol in which the methylene hydrogens are substituted by ethyl and 2-chlorovinyl groups. A hypnotic and sedative, it is used for treatment of insomnia in some cases where an intolerance or allergy to more commonly used drugs exists.
[Brand name] Placidyl (Abbott).

Safety Data	Back Directory
[Symbol(GHS) ] GHS06
[Signal word ] Danger
[Hazard statements ] H301
[Precautionary statements ] P264-P270-P301+P310-P321-P330-P405-P501
[HS Code ] 2905510000
[Safety Profile] Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Human systemic effects by ingestion: general anesthesia and thrombocytopenia (reduction in the number of blood platelets). Human effects on newborn by an unspecified route: drug dependency and Apgar score (condtion of newborn). Experimental teratogenic and reproductive effects. When heated to decomposition it emits toxic fumes of Cl-.
[Toxicity] LD50 in mice (mg/kg): 290 orally; 240 s.c. (P'an)

Tags:113-18-8 Related Product Information

54407-47-5 4187-86-4 77-75-8 918-85-4 3230-69-1

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