| Identification | Back Directory | [Name]
Tripolin A | [CAS]
1148118-92-6 | [Synonyms]
Tripolin A
Tripolin A ((E)-Tripolin A)
(3E)-3-[(2,5-Dihydroxyphenyl)methylene]-1,3-dihydro-2H-indol-2-one
2H-Indol-2-one, 3-[(2,5-dihydroxyphenyl)methylene]-1,3-dihydro-, (3E)- | [Molecular Formula]
C15H11NO3 | [MOL File]
1148118-92-6.mol | [Molecular Weight]
253.25 |
| Chemical Properties | Back Directory | [Melting point ]
265℃ (decomposition) | [Boiling point ]
584.9±50.0 °C(Predicted) | [density ]
1.441±0.06 g/cm3(Predicted) | [form ]
solid | [pka]
9.66±0.48(Predicted) | [color ]
Yellow |
| Hazard Information | Back Directory | [Uses]
Tripolin A ((E)-Tripolin A) is a specific non-ATP competitive Aurora A kinase inhibitor, with IC50 values of 1.5 μM and 7 μM for Aurora A and Aurora B, respectively[1]. | [storage]
+4°C | [References]
[1] Iliana A Kesisova, et al. Tripolin A, a Novel Small-Molecule Inhibitor of Aurora A Kinase, Reveals New Regulation of HURP's Distribution on Microtubules. PLoS One. 2013;8(3):e58485. DOI:10.1371/journal.pone.0058485 |
|
| Company Name: |
Abcam Limited
|
| Tel: |
+1 (877) 774-8286 |
| Website: |
http://www.abcam.com |
| Company Name: |
MedChemExpress
|
| Tel: |
021-58955995 |
| Website: |
www.medchemexpress.com |
|