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ChemicalBook--->CAS DataBase List--->119400-86-1

119400-86-1

119400-86-1 Structure

119400-86-1 Structure
IdentificationBack Directory
[Name]

9H-Cyclohepta[a]naphthalen-9-one,1,2,3,4- tetrahydro-10-hydroxy-4,4,8-trimethyl-
[CAS]

119400-86-1
[Synonyms]

Salviolone
Salvianolone
1,2,3,4-Tetrahydro-10-hydroxy-4,4,8-trimethyl-9H-cyclohepta[a]naphthalen-9-one
9H-Cyclohepta[a]naphthalen-9-one,1,2,3,4- tetrahydro-10-hydroxy-4,4,8-trimethyl-
9H-Cyclohepta[a]naphthalen-9-one,1,2,3,4- tetrahydro-10-hydroxy-4,4,8-trimethyl- USP/EP/BP
[Molecular Formula]

C18H20O2
[MDL Number]

MFCD21333449
[MOL File]

119400-86-1.mol
[Molecular Weight]

268.35
Chemical PropertiesBack Directory
[Melting point ]

180-182 °C
[Boiling point ]

461.2±45.0 °C(Predicted)
[density ]

1.140±0.06 g/cm3(Predicted)
[solubility ]

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
[form ]

cryst.
[pka]

7.94±0.40(Predicted)
[color ]

Yellow
Hazard InformationBack Directory
[Uses]

Salviolone is a natural diterpenoid derivative that can against melanoma cells. Salviolone exhibits a pleiotropic effect against melanoma by hampering cell cycle progression, STAT3 signaling, and malignant phenotype of A375 melanoma cells[1].
[References]

[1] Valentina Zanrè, et al. Salviolone from Salvia miltiorrhiza Roots Impairs Cell Cycle Progression, Colony Formation, and Metalloproteinase-2 Activity in A375 Melanoma Cells: Involvement of P21(Cip1/Waf1) Expression and STAT3 Phosphorylation. Int J Mol Sci. 2022 Jan 20;23(3):1121. DOI:10.3390/ijms23031121
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