Identification | Back Directory | [Name]
9H-Cyclohepta[a]naphthalen-9-one,1,2,3,4- tetrahydro-10-hydroxy-4,4,8-trimethyl- | [CAS]
119400-86-1 | [Synonyms]
Salviolone Salvianolone 1,2,3,4-Tetrahydro-10-hydroxy-4,4,8-trimethyl-9H-cyclohepta[a]naphthalen-9-one 9H-Cyclohepta[a]naphthalen-9-one,1,2,3,4- tetrahydro-10-hydroxy-4,4,8-trimethyl- 9H-Cyclohepta[a]naphthalen-9-one,1,2,3,4- tetrahydro-10-hydroxy-4,4,8-trimethyl- USP/EP/BP | [Molecular Formula]
C18H20O2 | [MDL Number]
MFCD21333449 | [MOL File]
119400-86-1.mol | [Molecular Weight]
268.35 |
Chemical Properties | Back Directory | [Melting point ]
180-182 °C | [Boiling point ]
461.2±45.0 °C(Predicted) | [density ]
1.140±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
cryst. | [pka]
7.94±0.40(Predicted) | [color ]
Yellow |
Hazard Information | Back Directory | [Uses]
Salviolone is a natural diterpenoid derivative that can against melanoma cells. Salviolone exhibits a pleiotropic effect against melanoma by hampering cell cycle progression, STAT3 signaling, and malignant phenotype of A375 melanoma cells[1]. | [References]
[1] Valentina Zanrè, et al. Salviolone from Salvia miltiorrhiza Roots Impairs Cell Cycle Progression, Colony Formation, and Metalloproteinase-2 Activity in A375 Melanoma Cells: Involvement of P21(Cip1/Waf1) Expression and STAT3 Phosphorylation. Int J Mol Sci. 2022 Jan 20;23(3):1121. DOI:10.3390/ijms23031121 |
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