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ChemicalBook--->CAS DataBase List--->1246303-06-9

1246303-06-9

1246303-06-9 Structure

1246303-06-9 Structure
IdentificationBack Directory
[Name]

1,2-dipalMitoyl-sn-glycero-3-[phospho-rac-(3-lysyl(1-glycerol))] (chloride salt)
[CAS]

1246303-06-9
[Synonyms]

16:0 Lysyl PG
1,2-dipalmitoyl-sn-glycero-3-[phospho-rac-(3-lysyl(1-glycerol))] (chloride salt)
1,2-DIPALMITOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(3-LYSYL(1-GLYCEROL))] (CHLORIDE SALT);16:0 LYSYL PG
1,2-dipalMitoyl-sn-glycero-3-[phospho-rac-(3-lysyl(1-glycerol))] (chloride salt)
1,2-DIPALMITOYL-SN-GLYCERO-3-[PHOSPHO-RAC-(3-LYSYL(1-GLYCEROL))] (CHLORIDE SALT);16:0 LYSYL PG
[Molecular Formula]

C44H88ClN2O11P
[MDL Number]

MFCD22416793
[MOL File]

1246303-06-9.mol
[Molecular Weight]

887.61
Chemical PropertiesBack Directory
[storage temp. ]

-20°C
[form ]

powder
Hazard InformationBack Directory
[Uses]

16:0 Lysyl PG is suitable for use:
  • as a standard for lipidomics analysis by using three-dimensional hydrophilic interaction liquid chromatography-ion mobility-mass spectrometry (HILIC-IM-MS)
  • to analyse the influence of peptides on the phase transition behavior of lipids by fourier transform infrared spectroscopy
  • in the preparation of artificial vesicles modelled on the lipid composition of Staphylococcal membranes to study the effect of galloyl catechins

[Biological Activity]

Lysyl phosphatidylglycerol (Lysyl-PG) is formed by lysinylation of PG in the presence of multiprotein resistance factor (MprF). MprF flips lysyl-PG from inner to outer membrane leafletincreasing the positive charge on the membrane. Lysyl PG is essential for domain formation and antibiotic resistance.
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