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ChemicalBook--->CAS DataBase List--->1261432-05-6

1261432-05-6

1261432-05-6 Structure

1261432-05-6 Structure
IdentificationBack Directory
[Name]

N-Desethylsunitinib hydrochloride
[CAS]

1261432-05-6
[Synonyms]

N-Desethyl sunitinib HCl
N-Desethylsunitinib hydrochloride
N Desethylsunitinib hydrochloride,NDesethylsunitinib hydrochloride
[Molecular Formula]

C20H24ClFN4O2
[MOL File]

1261432-05-6.mol
[Molecular Weight]

406.89
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Yellow to brown
Hazard InformationBack Directory
[Uses]

(E/Z)-N-Desethylsunitinib hydrochloride ((E/Z)-SU-12662 hydrochloride) is a compound with potential anti-tumor activity that inhibits VEGF-R2 and PDGF-Rβ tyrosine kinases. (E/Z)-N-Desethylsunitinib hydrochloride is the main active metabolite of sunitinib and has the ability to competitively inhibit ATP[1].
[References]

[1] Discovery of 5-[5-fluoro-2-oxo-1,2- dihydroindol-(3Z)-ylidenemethyl]-2,4- dimethyl-1H-pyrrole-3-carboxylic acid (2-diethylaminoethyl)amide, a novel tyrosine kinase inhibitor targeting vascular endothelial and platelet-derived growth factor receptor tyrosine kinase DOI:10.1021/jm0204183
Spectrum DetailBack Directory
[Spectrum Detail]

N-Desethylsunitinib hydrochloride(1261432-05-6)1HNMR
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