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ChemicalBook--->CAS DataBase List--->126869-52-1

126869-52-1

126869-52-1 Structure

126869-52-1 Structure
IdentificationBack Directory
[Name]

RM 06
[CAS]

126869-52-1
[Synonyms]

RM 06
N-[[5-(6-Hydroxy-9H-purin-9-yl)pentyloxy]carbonyl]-L-Leu-L-Met-OH
N-[[5-[(1,6-Dihydro-6-oxo-9H-purin)-9-yl]pentyloxy]carbonyl]-L-Leu-L-Met-OH
(2R)-2-[[(2S)-4-methyl-2-[5-(6-oxo-3H-purin-9-yl)pentoxycarbonylamino]pentanoyl]amino]-3-methylsulfanylpropanoic acid
[Molecular Formula]

C21H32N6O6S
[MDL Number]

MFCD00888011
[MOL File]

126869-52-1.mol
[Molecular Weight]

496.58
Hazard InformationBack Directory
[Description]

RM 06 is an immunomodulatory agent with a peptidyl-hypoxanthine structure.
[Uses]

RM 06 is an immunomodulator with a peptidyl hypoxanthine structure that significantly reduces the number of lung metastases of B16 melanoma cells in mice after lethal irradiation and bone marrow reconstitution by stimulating the activity of natural killer (NK) cells[1].
[Definition]

ChEBI: Omega-(Hypoxanthin-9-yl)-pentoxycarbonyl-leucyl-methionine is a dipeptide.
[References]

[1] Montaldo, et al. High-performance liquid chromatographic determination in human plasma of a new immunomodulatory agent with a peptidyl-hypoxanthine structure (RM 06). Journal of Chromatography B: Biomedical Sciences and Applications 525 (1990): 471-477. DOI:10.1016/s0378-4347(00)83426-x
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