天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook--->CAS DataBase List--->137778-20-2

137778-20-2

137778-20-2 Structure

137778-20-2 Structure
IdentificationBack Directory
[Name]

3-BroMo-2-Methylpyridine-6-carboxylic acid
[CAS]

137778-20-2
[Synonyms]

3-BroMo-2-Methylpyridine-6-carboxylic acid
5-Bromo-6-methyl-pyridine-2-carboxylic acid
2-Pyridinecarboxylic acid, 5-bromo-6-methyl-
[Molecular Formula]

C7H6BrNO2
[MDL Number]

MFCD13181588
[MOL File]

137778-20-2.mol
[Molecular Weight]

216.03
Chemical PropertiesBack Directory
[Boiling point ]

313.7±42.0 °C(Predicted)
[density ]

1.692±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,2-8°C
[pka]

3.48±0.10(Predicted)
[Appearance]

White to off-white Solid
[InChI]

InChI=1S/C7H6BrNO2/c1-4-5(8)2-3-6(9-4)7(10)11/h2-3H,1H3,(H,10,11)
[InChIKey]

UXKSXZKZOWOMKC-UHFFFAOYSA-N
[SMILES]

C1(C(O)=O)=NC(C)=C(Br)C=C1
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H312-H319-H332-H315-H302-H335
[Precautionary statements ]

P280-P302+P352-P312-P322-P363-P501-P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501
[HS Code ]

2933399990
Spectrum DetailBack Directory
[Spectrum Detail]

3-BroMo-2-Methylpyridine-6-carboxylic acid(137778-20-2)1HNMR
Hazard InformationBack Directory
[Synthesis]

5-Bromo-6-methyl-2-pyridinecarbonitrile

1173897-86-3

3-BroMo-2-Methylpyridine-6-carboxylic acid

137778-20-2

The general procedure for the synthesis of 5-bromo-6-methylpyridine-2-carboxylic acid from 5-bromo-6-methyl-2-cyanopyridine is as follows: 1. 5-bromo-6-methyl-2-cyanopyridine (18 kg, 91.37 mol), sodium hydroxide (10 kg, 250 mol), water (26 kg) and methanol (59 kg) were added sequentially in a stainless steel reactor. 2. the mixture was stirred and heated to reflux temperature (66 °C) and the reaction was kept for 1.52 hours. 3. the progress of the reaction was monitored by high performance liquid chromatography (HPLC) and the reaction was stopped when the amount of raw material remaining was less than 1%. 4. the solvent was removed by distillation under reduced pressure at a temperature below 50 °C. The solvent was then concentrated into the residue. 5. after thickening, water (72 kg) was added to the residue and the mixture was cooled to 0 °C. the reaction was stopped when the remaining amount of the feedstock was less than 1%. 6. The pH is adjusted to 7 by slow addition of sulfuric acid (105 kg) to induce precipitation of the product. 7. The precipitate was separated by centrifugation and washed with an appropriate amount of water. 8. The resulting solid was dried in a vacuum drying oven to give the white solid product 5-bromo-6-methylpyridine-2-carboxylic acid (17.8 kg, 82.3 mol). The purity of the product was greater than 98% and the yield was 90%.

[References]

[1] Patent: US2010/305330, 2010, A1. Location in patent: Page/Page column 3
137778-20-2 suppliers list
Company Name: Accela ChemBio Inc.
Tel: +1-858-6993322
Website: www.accelachem.com/
Company Name: Shandong chuangyingchemical Co., Ltd.
Tel: 18853181302
Website: www.approvedhomemanagement.com/ShowSupplierProductsList103425/0_EN.htm
Company Name: Alchem Pharmtech,Inc.
Tel: 8485655694
Website: www.approvedhomemanagement.com/ShowSupplierProductsList454175/0_EN.htm
Company Name: Fuxin Pharmaceutical
Tel: +86-021-021-50872116 +8613122107989 , +8613122107989
Website: http://www.fuxinpharm.com
Company Name: Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
Tel: +8613580539051 , +8613580539051
Website: www.yuhengpharm.com
Company Name: Shanghai kingmorn biotechnology Co.,Ltd.
Tel: 021-62200788 15000569291 , 15000569291
Website: www.kingmorn.com
Company Name: Hangzhou Benoy Chemical Co., Ltd
Tel: +8617342059697 , +8617342059697
Website: http://www.beinuochem.com/index.php/Indexen/index
Company Name: Suzhou Victorypharm Co.,Ltd.
Tel: +86-13916956214 , +86-13916956214
Website: http://www.victory-pharm.com/
Company Name: Suzhou Laing Biotechnology Co.,Ltd
Tel: +86-13004516015 +86-18149392822 , +86-18149392822
Website: http://en.laingbiotec.com/
Company Name: Coresyn Pharmatech Co., Ltd.
Tel: +86-571-86626709 +86-18157142896 , +86-18157142896
Website: http://www.coresyn.com/
Company Name: Tianjin Xinghan Biotechnology Co., Ltd
Tel: +8618698089028 , +8618698089028
Website: www.approvedhomemanagement.com/ShowSupplierProductsList662237/0_EN.htm
Company Name: Allsino Pharmaceutical Co.,Ltd
Tel: +86-571-88180350 +86-13588846430 , +86-13588846430
Website: http://www.allsino.com/
Company Name: Protheragen-ING
Tel: +16313385890 , +16313385890
Website: https://www.protheragen-ing.com/
Company Name: LEAPCHEM CO., LTD.
Tel: +86-852-30606658
Website: www.leapchem.com
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: +undefined18143011203 , +undefined18143011203
Website: www.chemextension.com/
Company Name: Aladdin Scientific
Tel:
Website: www.aladdinsci.com/
Company Name: Suzhou ARTK Medchem Co., Ltd.
Tel: +86-512-68323658 +86-18168183658 , +86-18168183658
Website:
Company Name: Cochemical Co. Ltd.
Tel: +86-029-86115547 +86-17791676824 , +86-17791676824
Website: www.cochemical.com
Tags:137778-20-2 Related Product Information
884495-14-1 886373-28-0 945557-04-0 1189513-51-6 114042-02-3 911434-05-4 164513-38-6 31181-90-5

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.