| Identification | Back Directory | [Name]
14,16,18,20,24,26-Hexahydroxy-2,3,15,27-tetramethyl-1-oxacyclooctacosa-4,6,8,10,12 -pentaen-28-one | [CAS]
141443-39-2 | [Synonyms]
AB023a
14,16,18,20,24,26-Hexahydroxy-2,3,15,27-tetramethyl-1-oxacyclooctacosa-4,6,8,10,12 -pentaen-28-one
Oxacyclooctacosa-17,19,21,23,25-pentaen-2-one, 4,6,10,12,14,16-hexahydroxy-3,15,27,28-tetramethyl- (9CI) | [Molecular Formula]
C31H50O8 | [MDL Number]
MFCD00918120 | [MOL File]
141443-39-2.mol | [Molecular Weight]
550.72 |
| Hazard Information | Back Directory | [Uses]
Antibiotic AB023a is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023b (HY-137085). Antibiotic AB023a exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea (MIC= 5 μg/mL), Fusarium moniliforme and Pythium ultimum[1][2]. | [References]
[1] Cidaria D, et al., AB023, novel polyene antibiotics. I. Taxonomy of the producing organism, fermentation and antifungal activity. J Antibiot (Tokyo). 1993 Feb;46(2):251-4. DOI:10.7164/antibiotics.46.251 |
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