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ChemicalBook--->CAS DataBase List--->1433901-75-7

1433901-75-7

1433901-75-7 Structure

1433901-75-7 Structure
IdentificationBack Directory
[Name]

6-Chloro-4-phenyl-2-(1-piperidinyl)-3-(2H-tetrazol-5-yl)quinoline
[CAS]

1433901-75-7
[Synonyms]

RO6806051
6-Chloro-4-phenyl-2-(1-piperidinyl)-3-(2H-tetrazol-5-yl)quinoline
Quinoline, 6-chloro-4-phenyl-2-(1-piperidinyl)-3-(2H-tetrazol-5-yl)-
RO6806051 6-chloro-4-phenyl-2-(piperidin-1-yl)-3-(1H-tetrazol-5-yl)quinoline
[Molecular Formula]

C21H19ClN6
[MOL File]

1433901-75-7.mol
[Molecular Weight]

390.87
Chemical PropertiesBack Directory
[Boiling point ]

652.9±65.0 °C(Predicted)
[density ]

1.349±0.06 g/cm3(Predicted)
[form ]

Solid
[pka]

1.88±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

RO6806051 (compound12) is a potent dual fatty acid binding protein 4 and 5 (FABP4 and FABP5) inhibitor with good selectivity and absorption, distribution, metabolism and excretion (eADME) properties[1].
[References]

[1] Kühne H, et al. Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors. Bioorg Med Chem Lett. 2016 Oct 15;26(20):5092-5097. DOI:10.1016/j.bmcl.2016.08.071
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