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ChemicalBook--->CAS DataBase List--->1452458-70-6

1452458-70-6

1452458-70-6 Structure

1452458-70-6 Structure
IdentificationBack Directory
[Name]

(2S,5R)-7-oxo-2-((((R)-pyrrolidin-3-yl)oxy)carbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate
[CAS]

1452458-70-6
[Synonyms]

(2S,5R)-7-oxo-2-((((R)-pyrrolidin-3-yl)oxy)carbamoyl)-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate
[Molecular Formula]

C11H18N4O7S
[MOL File]

1452458-70-6.mol
[Molecular Weight]

350.35
Chemical PropertiesBack Directory
[density ]

1.68±0.1 g/cm3(Predicted)
[pka]

-4.59±0.18(Predicted)
Hazard InformationBack Directory
[Uses]

FPI-1465 acts a dual inhibitor of serine-β-Lactamases and Penicillin-binding proteins (PBPs).FPI-1465 inhibits PBP2 (IC50=1.0 μg/mL). FPI-1465 exhibits activity against β-lactamase CTX-M-15 and OXA-48 with Kds of 0.011 and 5.3 μM, respectively[1].
[References]

[1] Andrew M King,?et al. Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-β-Lactamases and Penicillin-Binding Proteins. ACS Chem Biol.?2016 Apr 15;11(4):864-8. DOI:10.1021/acschembio.5b00944
1452458-70-6 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
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Company Name: TargetMol Chemicals Inc.  
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