| Identification | Back Directory | [Name]
FR901465 | [CAS]
146478-73-1 | [Synonyms]
FR901465
DQTXAXNYLWRTPB-NTVXLVODSA-N
2-Pentenamide, 4-(acetyloxy)-N-[(2R,3R,5S,6S)-tetrahydro-2,5-dimethyl-6-[(2E,4E)-3-methyl-5-[(3R,4R,5R,7S,8R)-4,7,8-trihydroxy-7-methyl-1,6-dioxaspiro[2.5]oct-5-yl]-2,4-pentadien-1-yl]-2H-pyran-3-yl]-, (2Z,4S)- | [Molecular Formula]
C27H41NO9 | [MDL Number]
MFCD28347814 | [MOL File]
146478-73-1.mol | [Molecular Weight]
523.62 |
| Hazard Information | Back Directory | [Uses]
FR901465 is a potent anti-cancer and anti-tumor agent. FR901465 can be used for cancer research[1]. | [Definition]
ChEBI: A spiro-epoxide with potent cytotoxic activity against human tumour cells. It is isolated from Pseudomonas sp. no.2663. | [References]
[1] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. II. Activities against experimental tumors in mice and mechanism of action. J Antibiot (Tokyo). 1996 Dec;49(12):1204-11. DOI:10.7164/antibiotics.49.1204
[2] H Nakajima, et al. New antitumor substances, FR901463, FR901464 and FR901465. III. Structures of FR901463, FR901464 and FR901465. J Antibiot (Tokyo). 1997 Jan;50(1):96-9. DOI:10.7164/antibiotics.50.96
[3] Ratnakar N. Asolkar, et al. Discovery and Development of Natural Products for Pest Management. RETURN TO BOOKPREVCHAPTERNEXT |
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