Identification | Back Directory | [Name]
Cefcapene Pivoxil Hydrochloride | [CAS]
147816-23-7 | [Synonyms]
(6R,7R)-(Pivaloyloxy)methyl 7-((Z)-2-(2-aminothiazol-4-yl)pent-2-enamido)-3-((carbamoyloxy)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-(((2Z)-2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl)amino)-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, (6R,7R)- 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-(2-amino-4-thiazolyl)-1-oxo-2-pentenyl)amino)-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, monohydrochloride, (6R-(6alpha,7beta(Z)))- | [Molecular Formula]
C23H30ClN5O8S2 | [MDL Number]
MFCD01682041 | [MOL File]
147816-23-7.mol | [Molecular Weight]
604.096 |
Chemical Properties | Back Directory | [Melting point ]
158-164°C | [storage temp. ]
Inert atmosphere,Store in freezer, under -20°C | [solubility ]
DMSO (Slightly), Methanol (Slightly), Water (Sparingly) | [form ]
Solid | [color ]
White to Pale Beige |
Hazard Information | Back Directory | [Chemical Properties]
White to Off-White Solid | [Uses]
Antibacterial. Orally absorbed cephalosporin; ester prodrug of the active free acid metabolite, cefcapene. | [in vivo]
Cefcapene pivoxil hydrochloride (oral administration; 100mg/kg; 4 days) is effective against invasive BLNAR strains in mice lung, stimates peak antibiotic concentrations of 1 to 2 μg/ml?in the blood of mice from 30 to 120 min after intragastric administration[3]. Animal Model: | Four-week-old female C57BL/6J mice with bacterial suspension in BSG (1×109?CFU)[3] | Dosage: | 100 mg/kg | Administration: | Oral administration; 100mg/kg; 4 days | Result: | Was against?H. influenzae?colonization in mouse lung. |
| [IC 50]
β-lactam |
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Company Name: |
Ralington Pharma
|
Tel: |
+91-7948911722 +91-9687771722 |
Website: |
www.ralingtonpharma.com |
Company Name: |
LGM Pharma
|
Tel: |
1-(800)-881-8210 |
Website: |
www.lgmpharma.com |
Company Name: |
Energy Chemical
|
Tel: |
021-58432009 400-005-6266 |
Website: |
http://www.energy-chemical.com |
|