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ChemicalBook--->CAS DataBase List--->1497439-74-3

1497439-74-3

1497439-74-3 Structure

1497439-74-3 Structure
IdentificationBack Directory
[Name]

1mg
[CAS]

1497439-74-3
[Synonyms]

1mg
AD-8007
Sulfo-SMCC activated SureLight Peridinin-Chlorophyll Protein Complex (PerCP)
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

AD-8007 is an acetyl CoA synthase 2 (ACSS2) inhibitor that can cross the blood-brain barrier. AD-8007 can significantly reduce lipid storage and cell colony formation in vitro models, and increase tumor cell death. AD-8007 has anti-cancer activity and can be used in the research of breast cancer[1].
[References]

[1] Esquea E, et al. Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573073. DOI:10.1101/2023.12.22.573073
[2] Esquea E,et al. Discovery of novel brain permeable human ACSS2 inhibitors for blocking breast cancer brain metastatic growth. bioRxiv [Preprint]. 2023 Dec 23:2023.12.22.573073. DOI:10.1101/2023.12.22.573073
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