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ChemicalBook--->CAS DataBase List--->15148-80-8

15148-80-8

15148-80-8 Structure

15148-80-8 Structure
IdentificationBack Directory
[Name]

3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride
[CAS]

15148-80-8
[Synonyms]

B 1312
KL 255
Looser
Panimit
Betadran
dl-KL 255
Betadrenol
SKF 16805A
(-)-KL 255
(+-)-Kl 255
Betadrenol hydrochloride
dl-Bupranolol hydrochloride
1-tert-Butylamino-3-(6-chloro-m-tolyloxy)-2-propanol hydrochloride
3-(tert-butylamino)-1-[(6-chloro-m-tolyl)oxy]propan-2-ol hydrochloride
1-(6'-Chloro-3'-methylphenoxy)-3-tert-butylaminopropanol, hydrochloride
3-tert-Butylamino-1-(6-chloro-3-methylphenoxy)propan-2-ol hydrochloride
1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanol hydrochloride
2-Propanol, 1-(tert-butylamino)-3-[(6-chloro-m-tolyl)oxy]-, hydrochloride (8CI)
2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, hydrochloride
[EINECS(EC#)]

239-208-3
[Molecular Formula]

C14H23Cl2NO2
[MOL File]

15148-80-8.mol
[Molecular Weight]

308.244
Chemical PropertiesBack Directory
[Melting point ]

220-222°
Hazard InformationBack Directory
[Uses]

Bupranolol hydrochloride is a non-selective β-adrenergic blocker with potent membrane stabilizing activity. Bupranolol hydrochloride is able to significantly modulate the contractile activity of the non-pregnant human uterus. Bupranolol hydrochloride showed significant effects on spontaneous uterine contractions in an in vitro study in patients with ovarian cancer. Bupranolol hydrochloride is similar in potency to propranolol, another β-adrenergic blocker. Bupranolol hydrochloride is rapidly and completely absorbed in vivo, and its major metabolite is carboxybupranolol[1].
[Definition]

ChEBI: Bupranolol hydrochloride is an aromatic ether.
[References]

[1] Myometrial Responses to Beta-Adrenoceptor Antagonists in Gynecological Malignancies DOI:10.1159/000513718
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