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ChemicalBook--->CAS DataBase List--->158227-81-7

158227-81-7

158227-81-7 Structure

158227-81-7 Structure
IdentificationBack Directory
[Name]

D-Ribitol, 1-C-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-1,4-anhydro-, (1S)-
[CAS]

158227-81-7
[Synonyms]

Antiviral agent 17
D-?Ribitol, 1-?C-?(4-?aminopyrrolo[2,?1-?f]?[1,?2,?4]?triazin-?7-?yl)?-?1,?4-?anhydro-?, (1S)?-
(2S,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
[Molecular Formula]

C11H14N4O4
[MDL Number]

MFCD32697107
[MOL File]

158227-81-7.mol
[Molecular Weight]

266.26
Chemical PropertiesBack Directory
[density ]

1.90±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

13.39±0.70(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Antiviral agent 17 (Compound 4) is an anti-infection agent. Antiviral agent 17 retains its antiviral effect in a human replicon assay (EC50 = 0.015 μM). Antiviral agent 17 results in good antiviral activity against murine norovirus. Antiviral agent 17 has the potential for the research of infectious and malignant diseases[1].
[References]

[1] Li Q, et al. Anti-norovirus activity of C7-modified 4-amino-pyrrolo[2,1-f][1,2,4]triazine C-nucleosides. Eur J Med Chem. 2020 Jun 1;195:112198. DOI:10.1016/j.ejmech.2020.112198
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