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ChemicalBook--->CAS DataBase List--->1606160-40-0

1606160-40-0

1606160-40-0 Structure

1606160-40-0 Structure
IdentificationBack Directory
[Name]

hoi-07
[CAS]

1606160-40-0
[Synonyms]

hoi-07
(Z)-3-((E)-4-(benzo[d][1,3]dioxol-5-yl)-2-oxobut-3-enylidene)indolin-2-one
2H-Indol-2-one, 3-[4-(1,3-benzodioxol-5-yl)-2-oxo-3-buten-1-ylidene]-1,3-dihydro-
[Molecular Formula]

C19H13NO4
[MDL Number]

MFCD26961115
[MOL File]

1606160-40-0.mol
[Molecular Weight]

319.31
Hazard InformationBack Directory
[Description]

HOI-07 is a specific Aurora B inhibitor.
[Uses]

(E/Z)-HOI-07 is a potent and selective Aurora B inhibitor. HOI-07 has antitumor activity[1].
[References]

[1] Xie H, et al. Identification of an Aurora kinase inhibitor specific for the Aurora B isoform. Cancer Res. 2013 Jan 15;73(2):716-24. DOI:10.1158/0008-5472.CAN-12-2784
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