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ChemicalBook--->CAS DataBase List--->163712-68-3

163712-68-3

163712-68-3 Structure

163712-68-3 Structure
IdentificationBack Directory
[Name]

XGZZHZMWIXFATA-VQNNHZPYSA-N
[CAS]

163712-68-3
[Synonyms]

XGZZHZMWIXFATA-VQNNHZPYSA-N
2-Propenamide, N-[(5α,6β)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]-3-(3-furanyl)-N-methyl-, (Z)- (9CI)
(Z)-N-((4R,4aS,7R,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-2,3,4,4a,5,6,7,7a-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-yl)-3-(furan-3-yl)-N-methylacrylamide
[Molecular Formula]

C28H32N2O5
[MOL File]

163712-68-3.mol
[Molecular Weight]

476.57
Chemical PropertiesBack Directory
[Boiling point ]

700.7±60.0 °C(Predicted)
[density ]

1.41±0.1 g/cm3(Predicted)
[pka]

9.37±0.60(Predicted)
Hazard InformationBack Directory
[Uses]

2Z-Nalfurafine-d3 is the labeled analogue of 2Z-Nalfurafine (N255610), a geometric isomer of Nalfurafine (N255600), a on-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid κ-agonist activity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. Nalfurafine is a new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients.
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