| Identification | Back Directory | [Name]
[pThr3]-CDK5 Substrate | [CAS]
1670273-47-8 | [Synonyms]
PK-{pTHR}-PKKAKKL
[pThr3]-CDK5 Substrate | [Molecular Formula]
C53H100N15O15P | [MDL Number]
MFCD04974433 | [MOL File]
1670273-47-8.mol | [Molecular Weight]
1218.43 |
| Chemical Properties | Back Directory | [density ]
1.257±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [pka]
1.79±0.10(Predicted) | [Sequence]
Pro-Lys-{pTHR}-Pro-Lys-Lys-Ala-Lys-Lys-Leu |
| Hazard Information | Back Directory | [Uses]
[pThr3]-CDK5 Substrate is an effective Phospho-Thr3CDK5 Substrate. [pThr3]-CDK5 Substrate is derived from the sequence of the histone H1 peptide that docks in the active site of CDK5. [pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 μM[1]. | [References]
[1] Beaudette KN, et al. Substrate specificity characterization of a cdc2-like protein kinase purified from bovine brain. J Biol Chem. 1993 Oct 5;268(28):20825-30. PMID:8407912 |
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