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ChemicalBook--->CAS DataBase List--->177947-03-4

177947-03-4

177947-03-4 Structure

177947-03-4 Structure
IdentificationBack Directory
[Name]

Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)-
[CAS]

177947-03-4
[Synonyms]

L772
L-772
L 772
L-772,405
Benzeneethanol, 4-fluoro-β-[[1-[3-[5-(4H-1,2,4-triazol-4-yl)-1H-indol-3-yl]propyl]-4-piperidinyl]amino]-, (βR)-
[Molecular Formula]

C26H31FN6O
[MDL Number]

MFCD19105471
[MOL File]

177947-03-4.mol
[Molecular Weight]

462.57
Chemical PropertiesBack Directory
[Boiling point ]

706.3±70.0 °C(Predicted)
[density ]

1.32±0.1 g/cm3(Predicted)
[pka]

14.44±0.10(Predicted)
Hazard InformationBack Directory
[Description]

L-772,405 is a highly selective h5-HT(1D) receptor agonists.
[Uses]

L-772405 is a selective 5-HT1D receptor agonist with the Ki values of 318, 29 and > 1000 nM aganist guinea pig 5-HT1B receptor, guinea pig 5-HT1D receptor and rat 5-HT rransporter, respectively. L-772405 decreases the potassium-induced outflow of 5-HT with an IC50 value of 240 nM[1].
[References]

[1] Pullar IA, et al. The role of the 5-HT1D receptor as a presynaptic autoreceptor in the guinea pig. Eur J Pharmacol. 2004 Jun 16;493(1-3):85-93. DOI:10.1016/j.ejphar.2004.04.029
177947-03-4 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website: www.targetmol.com/
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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