| Identification | Back Directory | [Name]
2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-, hydrochloride (1:1) | [CAS]
179420-27-0 | [Synonyms]
CJ-13,610 hydrochloride
CJ-13,610 hydrochloride, 10 mM in DMSO
CJ 13,610 hydrochloride,CJ13,610 hydrochloride
2H-Pyran-4-carboxamide, tetrahydro-4-[3-[[4-(2-methyl-1H-imidazol-1-yl)phenyl]thio]phenyl]-, hydrochloride (1:1) | [Molecular Formula]
C22H24ClN3O2S | [MOL File]
179420-27-0.mol | [Molecular Weight]
429.96 |
| Hazard Information | Back Directory | [Uses]
CJ-13,610 (hydrochloride) is an orally active and potent nonredox-type 5-lipoxygenase inhibitor with an IC50 value of 0.07 μM. CJ-13,610 (hydrochloride) competes with activating LOOH at a regulatory LOOH-binding site with high affinity, thereby preventing 5-lipoxygenase catalysis. CJ-13,610 (hydrochloride) is promising for research of diseases related to elevated levels of 5-lipoxygenase such as inflammatory reactions, allergic asthma, various types of cancer and atherosclerosis[1]. | [References]
[1] Fischer L, et al. Molecular pharmacological profile of the nonredox-type 5-lipoxygenase inhibitor CJ-13,610. Br J Pharmacol. 2004 Jul;142(5):861-8. DOI:10.1038/sj.bjp.0705860 |
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Website: |
https://www.bocsci.com |
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