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ChemicalBook--->CAS DataBase List--->187402-73-9

187402-73-9

187402-73-9 Structure

187402-73-9 Structure
IdentificationBack Directory
[Name]

L-Phenylalanine, N-((2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbuty)-L-va lyl-
[CAS]

187402-73-9
[Synonyms]

N-((2s,3r)-3-Amino-2-Hydroxy-1-Oxo-4-Phenylbuty)-L- Va Lyl-L-Phenylalanine
L-Phenylalanine, N-[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-valyl-
L-Phenylalanine, N-((2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbuty)-L-va lyl-
N-[(2S,3R)-3-Amino-2-hydroxy-1-oxo-4-phenylbutyl]-L-valyl-L-phenylalanine: NSC 702307
(2S)-2-[[(2S)-2-[[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl]amino]-3-methylbutanoyl]amino]-3-phenylpropanoic acid
[Molecular Formula]

C24H31N3O5
[MDL Number]

MFCD01630899
[MOL File]

187402-73-9.mol
[Molecular Weight]

441.525
Chemical PropertiesBack Directory
[Melting point ]

188-191 °C
[Boiling point ]

784.3±60.0 °C(Predicted)
[density ]

1.234±0.06 g/cm3(Predicted)
[pka]

3.49±0.10(Predicted)
Hazard InformationBack Directory
[Description]

Phebestin is an inhibitor of aminopeptidase N, produced by Streptomyces sp. MJ716-m3.
[Uses]

Phebestin is a compound with antimalarial activity that has an inhibitory effect on Plasmodium and has shown good results in in vitro and in vivo experiments. It can also bind to related enzymes of Plasmodium.
[References]

[1] Antiplasmodial Activity Evaluation of a Bestatin-Related Aminopeptidase Inhibitor, Phebestin DOI:10.1128/aac.01606-22
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