天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook--->CAS DataBase List--->2010159-60-9

2010159-60-9

2010159-60-9 Structure

2010159-60-9 Structure
IdentificationBack Directory
[Name]

E3 ligase Ligand-Linker Conjugates 6 Free Base
[CAS]

2010159-60-9
[Synonyms]

VH032-PEG2-NH2
S)-AHPC-PEG2-NH2
(S,R,S)-AHPC-PEG2-NH2
PROTACs Related Compound 6
VHL Ligand-Linker Conjugates 3
(S,R,S)-AHPC-acetamido-O-C2-amine HCI
(S,R. S)-AHPC-PEG2-amine hydrochloride salt
E3 ligase Ligand-Linker Conjugates 6 Free Base
(S,R,S)-AHPC-PEG2-NH2 (E3 ligase Ligand-Linker Conjugates 6 Free Base)
(2S,4R)-1-((S)-2-(2-(2-(2-aminoethoxy)ethoxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
(2S,4R)-1-[(2S)-2-[[2-[2-(2-aminoethoxy)ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
[Molecular Formula]

C28H41N5O6S
[MDL Number]

MFCD31728145
[MOL File]

2010159-60-9.mol
[Molecular Weight]

575.73
Chemical PropertiesBack Directory
[Boiling point ]

856.9±65.0 °C(Predicted)
[density ]

1.249±0.06 g/cm3(Predicted)
[solubility ]

Soluble in Water, DMSO, Methanol
[form ]

Solid
[pka]

13.54±0.46(Predicted)
[color ]

Off-white to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[HS Code ]

2934100090
Hazard InformationBack Directory
[Description]

(S, R, S)-AHPC-PEG2-amine is a synthetic PROTAC linker that incorporates an E3 ligase ligand with a PEG2 unit to empower drug research & discovery. It is reactive with NHS ester or carboxylic acid.
[Uses]

(S,R,S)-AHPC-PEG2-NH2 (VH032-PEG2-NH2) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTACs[1].
[IC 50]

VHL
[References]

[1] Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Me DOI:10.1021/acs.jmedchem.6b01912
2010159-60-9 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website: www.targetmol.com/
Company Name: Hebei Chuanghai Biotechnology Co., Ltd
Tel: +8615531151365 , +8615531151365
Website: www.chuanghaibio.com
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology
Tel: +undefined18143011203 , +undefined18143011203
Website: www.chemextension.com/
Company Name: Xian confluore Biological Technology Co., Ltd.
Tel: +86-15680926068 +86-15680926068 , +86-15680926068
Website: http://www.confluore.com/
Company Name: Aladdin Scientific
Tel:
Website: www.aladdinsci.com/
Company Name: Daicel Chiral Technologies (China)CO.,LTD  
Tel: 021-50460086-9 15921403865
Website: http://www.daicelchiraltech.cn/reagents/Default.aspx
Company Name: Aikon International Limited  
Tel: 025-58859352 18068836627
Website: www.aikonchem.com
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
Tel: +86-156-80926068 +86-15680926068
Website: http://www.confluore.cn/
Company Name: Shanghai SPAR pharmaceutical technology co., LTD  
Tel: 021-000000
Website: www.approvedhomemanagement.com/showsupplierproductslist30714/0.htm
Company Name: Jilin Province Woda Biotechnology Co., Ltd.  
Tel: 13504435624
Website: https://www.wodapro.com
Company Name: Nanjing Shizhou Biology Technology Co.,Ltd  
Tel: 025-85563444 18351873721
Website: http://www.synzest.com
Company Name: Zhengzhou Akem Chemical Co., Ltd  
Tel: 13303867194
Website: http://acmechem.cn/
Company Name: Shanghai Haohong Pharmaceutical Co., Ltd.  
Tel: 400-8210725 4008210725
Website: www.leyan.com/
Company Name: Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd  
Tel: 0431-80514535 19917294565
Website: www.chemextension.com
Company Name: Wuhan Yuxiang Medical Technology Co., Ltd.  
Tel: 13971275651
Website: http://www.approvedhomemanagement.com/ShowSupplierProductsList1155268/0.htm
Company Name: Xianning Shen Lan Biomedical Research and Development Co., Ltd.  
Tel: 18171815831
Website: http://www.shenlansw.com/
Company Name: ShenZhen Trendseen Biological Technology Co.,Ltd.  
Tel: 13417589054 13417589054
Website: www.approvedhomemanagement.com/showsupplierproductslist312717/0.htm
Company Name: Nanjing Bic Biotechnology Co., Ltd  
Tel: 025-58906079 17352406906
Website: www.bicbiotech.com/
Tags:2010159-60-9 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.