| Identification | Back Directory | [Name]
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB | [CAS]
2055042-69-6 | [Synonyms]
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB USP/EP/BP | [Molecular Formula]
C60H66N6O11 | [MDL Number]
MFCD30182025 | [MOL File]
2055042-69-6.mol | [Molecular Weight]
1047.22 |
| Questions And Answer | Back Directory | [Uses]
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | [In vitro]
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.MCE has not independently confirmed the accuracy of these methods. They are for reference only. | [Storage]
Please store the product under the recommended conditions in the Certificate of Analysis. |
| Hazard Information | Back Directory | [Description]
Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB PAB is a unique peptide cleavable ADC linker for antibody-drug-conjugation, PEG spacer increases the aqueous solubility. | [IC 50]
Cleavable Linker | [References]
[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
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| Company Name: |
Abydos Scientific
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| Tel: |
025-84767922 18936879710 |
| Website: |
http://www.abydoscientific.com/index.html |
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