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ChemicalBook--->CAS DataBase List--->2055896-92-7

2055896-92-7

2055896-92-7 Structure

2055896-92-7 Structure
IdentificationBack Directory
[Name]

MC-Val-Cit-PAB-vinblastine
[CAS]

2055896-92-7
[Synonyms]

MC-Val-Cit-PAB-vinblastine
[Molecular Formula]

C74H97N10O15+
[MDL Number]

MFCD32201115
[MOL File]

2055896-92-7.mol
[Molecular Weight]

1366.64
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to light brown
Hazard InformationBack Directory
[Uses]

MC-Val-Cit-PAB-vinblastine is a agent-linker conjugate for ADC with potent antitumor activity by using vinblastine (an microtubule protein inhibitor), linked via the ADC linker MC-Val-Cit-PAB.
[IC 50]

Traditional Cytotoxic Agents
[References]

[1] Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119. DOI:10.1038/nchem.2635
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