| Identification | Back Directory | [Name]
Biotin-PEG8-acid | [CAS]
2143964-62-7 | [Synonyms]
Biotin-PEG8-acid
(+)-Biotin-PEG8-CH2CH2COOH | [Molecular Formula]
C29H53N3O12S | [MDL Number]
MFCD26127802 | [MOL File]
2143964-62-7.mol | [Molecular Weight]
667.81 |
| Chemical Properties | Back Directory | [Boiling point ]
855.6±65.0 °C(Predicted) | [density ]
1.185±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
4.28±0.10(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Description]
Biotin-PEG8-acid is a biotin PEG linker containing a carboxylic acid group. The hydrophilic PEG spacer increase water solubility that is transferred to the biotinylated macromolecule. | [Uses]
Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329 |
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