| Identification | Back Directory | [Name]
MCL-1/BCL-2-IN-4 | [CAS]
2163793-56-2 | [Synonyms]
MCL-1/BCL-2-IN-4
MCL 1/BCL 2 IN 4,MCL1/BCL2IN4
Hexanoic acid, 6-[[2-[6-[(4-bromophenyl)thio]-1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl]ethyl]amino]-6-oxo- | [Molecular Formula]
C26H23BrN2O5S | [MDL Number]
MFCD32263423 | [MOL File]
2163793-56-2.mol | [Molecular Weight]
555.44 |
| Hazard Information | Back Directory | [Uses]
MCL-1/BCL-2-IN-4 (Compound 7) is a potent and selective Mcl-1 and Bcl-2 dual inhibitor[1]. | [References]
[1] Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163. DOI:10.1021/acs.jmedchem.9b00919 |
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