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ChemicalBook--->CAS DataBase List--->220094-15-5

220094-15-5

220094-15-5 Structure

220094-15-5 Structure
IdentificationBack Directory
[Name]

BOC-AEVD-CHO
[CAS]

220094-15-5
[Synonyms]

BOC-AEVD-CHO
BOC-ALA-GLU-VAL-ASP-CHO
BOC-ALA-GLU-VAL-ASP-ALDEHYDE
BOC-ALA-GLU-VAL-ASP-ALDEHYDE (PSEUDO ACID)
N-[(1,1-Dimethylethoxy)carbonyl]-L-alanyl-L-alpha-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]-L-valinamide
L-Valinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-L-α-glutamyl-N-[(1S)-2-carboxy-1-formylethyl]- (9CI)
[Molecular Formula]

C22H36N4O10
[MDL Number]

MFCD02259691
[MOL File]

220094-15-5.mol
[Molecular Weight]

516.54
Chemical PropertiesBack Directory
[density ]

1.258
[storage temp. ]

-15°C
Hazard InformationBack Directory
[Uses]

Boc-AEVD-CHO is a Caspase 8 inhibitor useful in the study of apoptosis and immune and inflammatory diseases[1][2].
[References]

[1] Garcia-Calvo M, et al. Inhibition of human caspases by peptide-based and macromolecular inhibitors. J Biol Chem. 1998 Dec 4;273(49):32608-13. DOI:10.1074/jbc.273.49.32608
[2] Grassmé H, et al. Ceramide-mediated clustering is required for CD95-DISC formation. Oncogene. 2003 Aug 21;22(35):5457-70. DOI:10.1038/sj.onc.1206540
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