| Identification | Back Directory | [Name]
2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride (1:1) | [CAS]
2222120-31-0 | [Synonyms]
3-(1-Oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2,6-dione hydrochloride
3-(l-oxo-5-(piperazin-1-yl)isoindolin-2-yl)piperidine-2, 6-dione hydrochloride
2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride
2,6-Piperidinedione, 3-[1,3-dihydro-1-oxo-5-(1-piperazinyl)-2H-isoindol-2-yl]-, hydrochloride (1:1) | [Molecular Formula]
C17H21ClN4O3 | [MDL Number]
MFCD32705051 | [MOL File]
2222120-31-0.mol | [Molecular Weight]
364.83 |
| Hazard Information | Back Directory | [Description]
CUN-20310 is a functionalized cereblon ligand for PROTAC? research and development; incorporates an E3 ligase ligand with a terminal piperazine for onward chemistry to generate Protein Degraders with rigid linkers. It is part of a range of functionalized tool molecules for PROTAC R&D. This product has no formal name. | [Uses]
Lenalidomide 5'-piperazine is a functionalized cerebellar ligand for PROTAC development that binds an E3 ligand to terminal piperazine for subsequent chemical reactions to produce a protein deactivator with a rigid linker[1]. | [IC 50]
Cereblon | [storage]
Store at -20°C | [References]
[1] Andrew P. Crew, et al. Cereblon ligands and bifunctional compounds comprising the same. WO2019199816A1.2019-10-17. |
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