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ChemicalBook--->CAS DataBase List--->2244684-42-0

2244684-42-0

2244684-42-0 Structure

2244684-42-0 Structure
IdentificationBack Directory
[Name]

VH 032, phenol
[CAS]

2244684-42-0
[Synonyms]

VH032-OH
VH 032, phenol
[Molecular Formula]

C24H32N4O5S
[MDL Number]

MFCD34368523
[MOL File]

2244684-42-0.mol
[Molecular Weight]

488.6
Chemical PropertiesBack Directory
[Boiling point ]

823.8±65.0 °C(Predicted)
[density ]

1.296±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[form ]

Solid
[pka]

9.12±0.35(Predicted)
[color ]

White to light yellow
Hazard InformationBack Directory
[Uses]

VH032-OH is the VH032-based VHL ligand. VH032-OH can be connected to the ligand for protein by a linker to form PROTACs[1].
[reaction suitability]

reagent type: ligand
[IC 50]

VHL
[storage]

Store at -20°C
[References]

[1] Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017;8(1):830. Published 2017 Oct 10. DOI:10.1038/s41467-017-00954-1
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