2410598-01-3

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2410598-01-3 Structure

Identification	Back Directory
[Name] Boc-NH-PEG10-CH2CH2COOH
[CAS] 2410598-01-3
[Synonyms] BocNH-PEG10-COOH Boc-NH-PEG10-CH2CH2COOH
[Molecular Formula] C28H55NO14
[MDL Number] MFCD27635164
[MOL File] 2410598-01-3.mol
[Molecular Weight] 629.74

Hazard Information	Back Directory
[Uses] Boc-NH-PEG10-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[Biological Activity] Boc-NH-PEG10-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[IC 50] PEGs; Alkyl/ether
[References] [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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