Identification | Back Directory | [Name]
Pyrazino[1',2':1,6]pyrido[3,4-b]indole-2(1H)-hexanamide, 6-(4-bromophenyl)-3,4,6,7,12,12a-hexahydro-N-hydroxy-1,4-dioxo-, (6S,12aS)- | [CAS]
2414921-46-1 | [Synonyms]
HDAC-IN-44 Pyrazino[1',2':1,6]pyrido[3,4-b]indole-2(1H)-hexanamide, 6-(4-bromophenyl)-3,4,6,7,12,12a-hexahydro-N-hydroxy-1,4-dioxo-, (6S,12aS)- | [Molecular Formula]
C26H27BrN4O4 | [MOL File]
2414921-46-1.mol | [Molecular Weight]
539.42 |
Hazard Information | Back Directory | [Uses]
HDAC-IN-44 is a HDAC inhibitor with the IC50 value of 61.2 nM. HDAC-IN-44 shows high anticancer activity towards multiple cancer cell lines[1]. | [References]
[1] Ahmed K ElHady et al. Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors. Bioorg Chem. 2020 May;98:103742. DOI:10.1016/j.bioorg.2020.103742 |
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