| Identification | Back Directory | [Name]
1H-Benzimidazole-6-carboxylic acid, 2-[[6-[(4-cyano-2-fluorophenyl)methoxy]-3',6'-dihydro[2,4'-bipyridin]-1'(2'H)-yl]methyl]-1-[(2S)-2-oxetanylmethyl]- | [CAS]
2428640-18-8 | [Synonyms]
GLP-1R agonist 3
1H-Benzimidazole-6-carboxylic acid, 2-[[6-[(4-cyano-2-fluorophenyl)methoxy]-3',6'-dihydro[2,4'-bipyridin]-1'(2'H)-yl]methyl]-1-[(2S)-2-oxetanylmethyl]- | [Molecular Formula]
C31H28FN5O4 | [MOL File]
2428640-18-8.mol | [Molecular Weight]
553.58 |
| Chemical Properties | Back Directory | [Boiling point ]
803.9±65.0 °C(Predicted) | [density ]
1.39±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
3.38±0.30(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
GLP-1R agonist 3 is a potent agonist of GLP-1R. GLP-1R agonist 3 is a thickened imidazole derivative compound. Glucagon-like peptide-1 (GLP-1) is an intestinal hypoglycemic hormone secreted by L-cells in the lower gastrointestinal tract. GLP-1R agonist 3 has the potential for the research of diabetes (extracted from patent WO2021197464A1, compound 1)[1]. | [References]
[1] Fanglong Yang, et al. Thickened imidazole derivatives, methods of their preparation and their application in medicine. Patent WO2021197464A1. |
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