| Identification | Back Directory | [Name]
Thiourea, N-(4-nitrophenyl)-N'-[1-[6-(trifluoromethyl)-2-pyridinyl]-4-piperidinyl]- | [CAS]
2477651-10-6 | [Synonyms]
DUN51106
USP8-IN-3
Thiourea, N-(4-nitrophenyl)-N'-[1-[6-(trifluoromethyl)-2-pyridinyl]-4-piperidinyl]- | [Molecular Formula]
C18H18F3N5O2S | [MOL File]
2477651-10-6.mol | [Molecular Weight]
425.43 |
| Chemical Properties | Back Directory | [Boiling point ]
548.6±60.0 °C(Predicted) | [density ]
1.45±0.1 g/cm3(Predicted) | [form ]
Solid | [pka]
11.18±0.70(Predicted) | [color ]
Light yellow to yellow |
| Hazard Information | Back Directory | [Uses]
USP8-IN-3 (Compd U51) is a deubiquitinase USP8 inhibitor with an IC50 value of 4.0 μM. USP8-IN-3 also inhibits the proliferation of GH3 and H1957 cells with GI50s of 37.03 μM and 6.01 μM, respectively[1]. | [IC 50]
USP8: 4.0 μM (IC50) | [References]
[1] Li zhiyun, et al. Preparing method and application of USP8 inhibitor: China, CN111138358 A. 2020-05-12. |
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| Company Name: |
InvivoChem
|
| Tel: |
13549236410 |
| Website: |
https://www.invivochem.cn/ |
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