| Identification | Back Directory | [Name]
Benzamide, N-[4-[(4-fluorobenzoyl)amino]phenyl]-3,4,5-trihydroxy- | [CAS]
2489813-02-5 | [Synonyms]
α-Synuclein inhibitor 6
Benzamide, N-[4-[(4-fluorobenzoyl)amino]phenyl]-3,4,5-trihydroxy- | [Molecular Formula]
C20H15FN2O5 | [MOL File]
2489813-02-5.mol | [Molecular Weight]
382.34 |
| Hazard Information | Back Directory | [Uses]
α-Synuclein inhibitor 6 (compound 3ge) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.70 μM and inhibition ratio at 30 μM of 94.4%[1]. | [IC 50]
α-synuclein Aggregation | [References]
[1] Chen L, et al. Amide derivatives of Gallic acid: Design, synthesis and evaluation of inhibitory activities against in vitro α-synuclein aggregation. Bioorg Med Chem. 2020 Aug 1;28(15):115596. DOI:10.1016/j.bmc.2020.115596 |
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