| Identification | Back Directory | [Name]
N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT | [CAS]
24967-27-9 | [Synonyms]
N-ACETYL-2 3-DEHYDRO-2-DEOXYNEURAMINIC &
2-deoxy-2,3-dehydro-n-acetylneuraminicacid
N-ACETYL-2,3-DEHYDRO-2-DEOXYNEURAMINIC ACID
1,3-DEHYDRO-2-DEOXY-N-ACETYLNEURAMINIC ACID
2,3-DEHYDRO-2-DEOXY-N-ACETYLNEURAMINIC ACID
N-acetyl-2,3-didehydro-2-deoxyneuraminic acid
2,3-Dehydro-2-deoxy-N-acetylneuraminic Acid
DANA
N-Acetyl-2,3-didehydro-2-deoxyneuraminic Acid >
N-Acetyl-2,3-didehydro-2-deoxyneuraminic Acid
N-ACETYL-2,3-DEHYDRO-2-DEOXYNEURAMINIC ACID SODIUM SALT
N-ACETYLNEURAMINIC ACID, 2,3-DEHYDRO-2-DEOXY-, SODIUM SALT
N-Acetyl-2,3-didehydro-2-deoxyneuraminic Acid, >98.0%(HPLC)
D-glycero-D-galacto-Non-2-enonic acid, 5-(acetylamino)-2,6-anhydro-3,5-dideoxy-
(4S,5R,6R)-5-ACETAMIDO-4-HYDROXY-6-[(1R,2R)-1,2,3-TRIHYDROXYPROPYL]-5,6-DIHYDRO-4H-PYRAN-2-CARBOXYLI
(2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid | [EINECS(EC#)]
246-550-7 | [Molecular Formula]
C11H17NO8 | [MDL Number]
MFCD00269867 | [MOL File]
24967-27-9.mol | [Molecular Weight]
291.25 |
| Chemical Properties | Back Directory | [Melting point ]
227-228 | [Boiling point ]
773.4±60.0 °C(Predicted) | [density ]
1.58±0.1 g/cm3(Predicted) | [storage temp. ]
−20°C
| [solubility ]
H2O: soluble50mg/mL, clear, colorless | [form ]
Solid | [pka]
3.90±0.70(Predicted) | [color ]
White to Pale Yellow | [biological source]
synthetic (organic) | [optical activity]
[α]20/D 40.8 to 51.0 °, c =0.66% (w/v) in water | [Water Solubility ]
water: 1mM | [BRN ]
8722455 | [CAS DataBase Reference]
24967-27-9 |
| Hazard Information | Back Directory | [Uses]
Neuraminidase (sialidase) inhibitor | [Definition]
ChEBI: N-Acetylneuraminic acid reduced across the 2,3-bond with loss of the hydroxy group at C-2; it is a minor component of body fluids although abundant in sialuria. | [Biological Activity]
Inhibitor of bacterialviral and animal neuraminidase (sialidase). | [in vivo]
N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) (10 mg/kg; i.p.; daily) attenuates pulmonary fibrosis in a mouse model[3]. | Animal Model: | Mice (Mouse model of pulmonary fibrosis)[3] | | Dosage: | 10?mg/kg | | Administration: | I.p.; daily (starting at day 10 after Bleomycin, and then euthanized at day 21) | | Result: | Inhibition of sialidases starting at day 10 after bleomycin attenuates fibrosis.
|
| [storage]
Store at -20°C |
|
| Company Name: |
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821-50328103-801 18930552037 |
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http://www.approvedhomemanagement.com/ShowSupplierProductsList13285/0.htm |
| Company Name: |
Energy Chemical
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021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
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