天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ChemicalBook--->CAS DataBase List--->2554620-04-9

2554620-04-9

2554620-04-9 Structure

2554620-04-9 Structure
IdentificationBack Directory
[Name]

Benzonitrile, 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-6,7-dimethoxy-2-quinazolinyl]amino]-
[CAS]

2554620-04-9
[Synonyms]

HIV-1 inhibitor-21
Benzonitrile, 4-[[4-[[4-[(1E)-2-cyanoethenyl]-2,6-dimethylphenyl]amino]-6,7-dimethoxy-2-quinazolinyl]amino]-
[Molecular Formula]

C28H24N6O2
[MOL File]

2554620-04-9.mol
[Molecular Weight]

476.53
Chemical PropertiesBack Directory
[Boiling point ]

705.1±70.0 °C(Predicted)
[density ]

1.31±0.1 g/cm3(Predicted)
[pka]

7.23±0.30(Predicted)
Hazard InformationBack Directory
[Uses]

HIV-1 inhibitor-21 (compound 9b) is a potent HIV-1 non-nucleoside reverse transcriptase (RT) inhibitor, with an IC50 value of 0.55 μM for HIV-1 RT. HIV-1 inhibitor-21 has antiretroviral activity against HIV-1 WT and K103N strains with EC50s of 12.7 nM and 10.4 nM, and has relatively low cytotoxicity (MT-4?cells CC50?=10.2?μM)[1].
[IC 50]

HIV-1 (WT): 12.7 nM (EC50); HIV-1 (K103N): 10.4 nM (EC50)
[References]

[1] Han S, et al. Fragment hopping-based discovery of novel sulfinylacetamide-diarylpyrimidines (DAPYs) as HIV-1 nonnucleoside reverse transcriptase inhibitors. Eur J Med Chem. 2020;185:111874. DOI:10.1016/j.ejmech.2019.111874
2554620-04-9 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: Nantong Hanfang Biotechnology Co. , Ltd.  
Tel: hanfangpharma@126.com; 18616537568
Website: https://hanfangpharma@126.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
Tags:2554620-04-9 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.