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ChemicalBook--->CAS DataBase List--->2738376-78-6

2738376-78-6

2738376-78-6 Structure

2738376-78-6 Structure
IdentificationBack Directory
[Name]

INDEX NAME NOT YET ASSIGNED
[CAS]

2738376-78-6
[Synonyms]

[Molecular Formula]

C25H35N3O6S
[MOL File]

2738376-78-6.mol
[Molecular Weight]

505.63
Chemical PropertiesBack Directory
[solubility ]

Acetonitrile: soluble; Methanol: soluble
[form ]

A solid
Safety DataBack Directory
[Symbol(GHS) ]


GHS08
[Signal word ]

Warning
[Hazard statements ]

H351-H361-H412
[Precautionary statements ]

P201-P202-P273-P280-P308+P313-P405-P501
Hazard InformationBack Directory
[Description]

Amprenavir-d4 is intended for use as an internal standard for the quantification of amprenavir by GC- or LC-MS. Amprenavir is an inhibitor of HIV protease (Ki = 0.04 nM).1 It inhibits the cytopathic effects of HIV-1 in MT-4 cells (IC50 = 150 nM). Formulations containing amprenavir have been used in combination with other antiretroviral agents in the treatment of HIV-1 infection.
[Uses]

Amprenavir-d4-1 is deuterium labeled Amprenavir. Amprenavir (VX-478) is a HIV protease inhibitor (Ki=0.6 nM) used to treat HIV infection. Amprenavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.09 μM.
[References]

1. Sherrill, R.G., Furfine, E.S., Hazen, R.J., et al. Synthesis and antiviral activities of novel N-alkoxy-arylsulfonamide-based HIV protease inhibitors Bioorg. Med. Chem. Lett. 15(15),3560-3564(2005).
2738376-78-6 suppliers list
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Website: www.caymanchem.com
Company Name: Cayman Chemical Company  
Tel: (800) 364-9897
Website: www.caymanchem.com
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