| Identification | Back Directory | [Name]
3-amino-5-(4-benzylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one | [CAS]
356568-70-2 | [Synonyms]
Barbadin
3-amino-5-(4-benzylphenyl)thieno[2,3-d]pyrimidin-4(3H)-one
Thieno[2,3-d]pyrimidin-4(3H)-one, 3-amino-5-[4-(phenylmethyl)phenyl]- | [Molecular Formula]
C19H15N3OS | [MDL Number]
MFCD01917483 | [MOL File]
356568-70-2.mol | [Molecular Weight]
333.41 |
| Chemical Properties | Back Directory | [Melting point ]
175-180°C | [Boiling point ]
539.8±60.0 °C(Predicted) | [density ]
1.34±0.1 g/cm3(Predicted) | [storage temp. ]
Refrigerator | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) | [form ]
Solid | [pka]
-1.88±0.20(Predicted) | [color ]
White to Pale Yellow |
| Hazard Information | Back Directory | [Uses]
Barbadin is a selective β-arrestin/β2-adaptin inhibitor. It selectively inhibits the interaction between b-arrestin and the b2-adaptin subunit of the clathrin adaptor protein AP2 without affecting the formation of receptor/b-arrestin complexes. | [Biological Activity]
selective b-arrestin/b2-adaptin inhibitor | [storage]
Store at -20°C |
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