| Identification | Back Directory | [Name]
METHYL 2-FLUORO-4-NITROBENZENECARBOXYLATE | [CAS]
392-09-6 | [Synonyms]
METHYL 2-FLUORO-4-NITROBENZOATE
3-Fluoro-4-(methoxycarbonyl)nitrobenzene
METHYL 2-FLUORO-4-NITROBENZENECARBOXYLATE
Benzoic acid, 2-fluoro-4-nitro-, Methyl ester | [EINECS(EC#)]
206-873-6 | [Molecular Formula]
C8H6FNO4 | [MDL Number]
MFCD08444028 | [MOL File]
392-09-6.mol | [Molecular Weight]
199.14 |
| Chemical Properties | Back Directory | [Melting point ]
73-75°C | [Boiling point ]
314.6±32.0 °C(Predicted) | [density ]
1.388 | [storage temp. ]
Sealed in dry,Room Temperature | [form ]
crystalline solid | [color ]
Pale lemon | [InChI]
InChI=1S/C8H6FNO4/c1-14-8(11)6-3-2-5(10(12)13)4-7(6)9/h2-4H,1H3 | [InChIKey]
KJCVCRCYCOWPFY-UHFFFAOYSA-N | [SMILES]
C(OC)(=O)C1=CC=C([N+]([O-])=O)C=C1F |
| Hazard Information | Back Directory | [Uses]
Methyl 2-fluoro-4-nitrobenzoate is a pharmaceutical intermediate compound used in the preparation of the anticancer drug Venetoclax. Venetoclax is a B-cell lymphoma-2 (BCL-2) inhibitor used in the treatment of adults with chronic lymphocytic leukaemia (CLL) or small lymphocytic lymphoma (SLL), or newly diagnosed chronic lymphocytic lymphoma (SLL). |
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