| Identification | Back Directory | [Name]
Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI) | [CAS]
406947-32-8 | [Synonyms]
BGT1-IN-1
3-Aminobicyclo[1.1.1]pentane-1-carboxylicacid
Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino-
Bicyclo[1.1.1]pentane-1-carboxylic acid, 3-amino- (9CI) | [Molecular Formula]
C6H9NO2 | [MDL Number]
MFCD18826734 | [MOL File]
406947-32-8.mol | [Molecular Weight]
127.14 |
| Hazard Information | Back Directory | [Uses]
BGT1-IN-1 (compound 9) is a potent BGT1 inhibitor with IC50 value of 13.9, 58.3 μM for hBGT1, GAT3, respectively. BGT1-IN-1 shows no cytotoxic. BGT1-IN-1 shows neuroprotective activity[1]. | [References]
[1] ??tka K, et al. Rational Search for Betaine/GABA Transporter 1 Inhibitors─In Vitro Evaluation of Selected Hit Compound. ACS Chem Neurosci. 2024 Oct 19. DOI:10.1021/acschemneuro.4c00425 |
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