| Identification | Back Directory | [Name]
5'-O-TERT-BUTYLDIMETHYLSILYL-THYMIDINE | [CAS]
40733-28-6 | [Synonyms]
5′-O-TBS dT
5'-TBDMS dT
5'-O-TBDMS-dT
5'-O-TBDMS-thymidine
5'-O-TBDMSoxy-thymidine
5'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE
5'-O-TERT-BUTYLDIMETHYLSILYL-THYMIDINE
5'-O-tert-Butyldimethylsilylthymidine 97%
5'-O-(tert-ButyldiMethylsilyl)thyMidine, 97+%
5'-O-(tert-ButyldiMethylsilyl)thyMidine, 98+%
5'-tert-butyldimethylsilyloxy-2'-deoxythymidine
Thymidine, 5'-O-[(1,1-dimethylethyl)dimethylsilyl]-
5-Methyl-5'-O-(tert-butyldimethylsilyl)-2'-deoxyuridine
1-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione | [Molecular Formula]
C16H28N2O5Si | [MDL Number]
MFCD01631041 | [MOL File]
40733-28-6.mol | [Molecular Weight]
356.49 |
| Chemical Properties | Back Directory | [Melting point ]
198 | [density ]
1.148±0.06 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [solubility ]
DMSO : 100 mg/mL (280.51 mM; Need ultrasonic) | [form ]
powder | [pka]
9.55±0.10(Predicted) | [color ]
White |
| Hazard Information | Back Directory | [Description]
5'-O-(tert-Butyldimethylsilyl)thymidine is a synthetic nucleoside that is used as an antiviral agent in the treatment of herpes zoster and other viral infections. 5'-O-tert-Butyldimethylsilyl-D3-thymidine is a novel monophosphate, which can be activated to a diphosphate by either kinases or phosphoramidites. It has been shown to be effective against herpes virus and other DNA viruses that infect cells from various species. | [Uses]
5'-O-(tert-Butyldimethylsilyl)thymidine is used as pharmaceutical intermediate. |
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