| Identification | Back Directory | [Name]
DIETHYL ISOCYANOMETHYLPHOSPHONATE | [CAS]
41003-94-5 | [Synonyms]
Diethyl (isocyanomethyl)
Diethyleisocyanomethylphosphonate
DIETHYL ISOCYANOMETHYLPHOSPHONATE
Diethoxyphosphinylmethyl isocyanide
Diethyl isocyanomethylphosphonate,97%
Diethyl isocyanomethylphosphonate 97%
[(Diethoxyphosphinyl)methyl] isocyanide
ISOCYANOMETHYL-PHOSPHONIC ACID DIETHYL ESTER
ISOCYANOMETHYLPHOSPHONONIC ACID DIETHYL ESTER | [Molecular Formula]
C6H12NO3P | [MDL Number]
MFCD00042951 | [MOL File]
41003-94-5.mol | [Molecular Weight]
177.14 |
| Chemical Properties | Back Directory | [Appearance]
Clear colorless to yellow liquid | [Boiling point ]
84-87 °C0.1 mm Hg(lit.)
| [density ]
1.105 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.433(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [form ]
Liquid | [color ]
Clear colorless to yellow | [BRN ]
4674920 | [CAS DataBase Reference]
41003-94-5 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colorless to yellow liquid | [Description]
Diethyl isocyanoMethylphosphonate is a reagent for the elongation of aldehydes and ketones with a one-carbon unit; connective reagent; N,P-acetals; reagent for the conversion of nitroalkenes into 2-pyrrolephosphonates. | [Uses]
Reactant for:
- Copper-catalyzed cycloaddition reactions
- Preparation of orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase
- Synthesis of sterol analogs as antifungal agents against plant pathogens
- Asymmetric synthesis of steroidal 2,5-diketopiperazines prepared via isocyanide chemistry based on stereoselective Ugi four component condensation and subsequent cyclocondensation reactions
- The Passerini reaction
| [reaction suitability]
reaction type: C-C Bond Formation | [Synthesis]
Diethyl isocyanoMethylphosphonate is prepared by dehydration of N-(diethoxyphosphorylmethyl)formamide. | [storage]
Stored for long periods of time at 0 °C or below |
|
| Company Name: |
Energy Chemical
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021-021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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