| Identification | Back Directory | [Name]
6-AMINO-9-[2-(4-ETHOXYPHENOXY)ETHYL]-9H-PURINE-8-THIOL | [CAS]
445416-12-6 | [Synonyms]
NSD3-IN-3
6-AMINO-9-[2-(4-ETHOXYPHENOXY)ETHYL]-9H-PURINE-8-THIOL
8H-Purine-8-thione, 6-amino-9-[2-(4-ethoxyphenoxy)ethyl]-7,9-dihydro- | [Molecular Formula]
C15H17N5O2S | [MDL Number]
MFCD03270800 | [MOL File]
445416-12-6.mol | [Molecular Weight]
331.39 |
| Hazard Information | Back Directory | [Uses]
NSD3-IN-3 is a potent NSD3 inhibtor with an IC50 value of 1.86 μM. NSD3-IN-3 has anticancer activity and significantly inhibits the growth and proliferation of non-small cell lung cancer cell line H460[1]. | [IC 50]
NSD3: 1.86 μM (IC50) | [References]
[1] Kong Ren, et al. Application of compound B2 as histone methyltransferase NSD3 inhibitor: China, CN109223795[P].2019-01-18. |
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