| Identification | Back Directory | [Name]
1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate | [CAS]
445441-27-0 | [Synonyms]
SGS 518 oxalate
1-Methyl-3-(1-methyl-4-piperindin-4-yl)-5-hydroxy-1H-indole2,6-difluorobenzenesulfonicacidesteroxalate | [Molecular Formula]
C23H24F2N2O7S | [MDL Number]
MFCD18384957 | [MOL File]
445441-27-0.mol | [Molecular Weight]
510.51 |
| Hazard Information | Back Directory | [Uses]
SGS 518 Oxalate is a 5-HT6 antgaonist. | [in vivo]
SGS518 oxalate (30 mg/kg; i.p. for 30 min) protects Abca4–/–Rdh8 sup>–/– mouse retinas from light-induced damage[1]. | Animal Model: | Abca4–/–Rdh8 sup>–/–mice are exposed at white light[1] | | Dosage: | 30 mg/kg | | Administration: | I.p. injection for 30 minutes | | Result: | A marked preservation of the photoreceptor layer.
Reduced formation of autofluorescent spots in mice.
Protected retinal morphology.
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| [IC 50]
5-HT6 Receptor |
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