Chemical Properties | Back Directory | [Melting point ]
193-194 °C | [Boiling point ]
668.4±40.0 °C(Predicted) | [density ]
1.09±0.1 g/cm3(Predicted) | [storage temp. ]
4°C, protect from light | [form ]
Solid | [pka]
8?+-.0.20(Predicted) | [color ]
White to off-white |
Hazard Information | Back Directory | [Uses]
24-Methylenecycloartanyl ferulate is a γ-oryzanol compound. 24-Methylenecycloartanyl ferulate promotes parvin-beta expression in human breast cancer cells. 24-Methylenecycloartanyl ferulate is a potential ATP-competitive Akt1 inhibitor (EC50= 33.3μM)[1]. | [IC 50]
Akt1: 33.3 μM (EC50) | [References]
[1] Heon Woong Kim, et al. 24-Methylenecycloartanyl ferulate, a major compound of γ-oryzanol, promotes parvin-beta expression through an interaction with peroxisome proliferator-activated receptor-gamma 2 in human breast cancer cells. Biochem Biophys Res Commun. 2015 Dec 25;468(4):574-9. DOI:10.1016/j.bbrc.2015.10.147 |
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