| Identification | Back Directory | [Name]
3-Benzofurancarboxylic acid, 5-[(1E)-2-carboxyethenyl]-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy- | [CAS]
503323-06-6 | [Synonyms]
Antileishmanial agent-7
3-Benzofurancarboxylic acid, 5-[(1E)-2-carboxyethenyl]-2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy- | [Molecular Formula]
C20H18O8 | [MOL File]
503323-06-6.mol | [Molecular Weight]
386.35 |
| Hazard Information | Back Directory | [Uses]
Antileishmanial agent-7 (compound 23) is a potent antileishmanial agent. Antileishmanial agent-7 shows antileishmanial activity against Leishmania donovani and L-6, with IC50 values of 6.89 and 259 μM, respectively[1]. | [References]
[1] Bernal FA, et al. (±)-trans-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: Synthesis, in vitro evaluation and SAR analysis. Eur J Med Chem. 2020 Nov 1;205:112493. DOI:10.1016/j.ejmech.2020.112493 |
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